ABSTRACT
RESUMOObjetivo:analisar concepções de enfermeiros sobre Vigilância em Saúde da Criança (VSC) em unidades de saúde da família.Métodos:estudo qualitativo, com análise temática dos dados, fundamentada no paradigma da Vigilância em Saúde. Foram realizadas entrevistas com 13 enfermeiros atuantes em município do interior paulista.Resultados:os enfermeiros conceberam VSC como acompanhamento ativo, integral, programado, identificando riscos/vulnerabilidades, por meio de ações multiprofissionais, intersetoriais e dependentes da participação materna. Constatou-se desenvolvimento parcial dessas premissas na prática, por dificuldades como falta de participação materna nas ações propostas, indisponibilidade de tempo para discussão e adoção de medidas nas unidades e desarticulação entre níveis e setores no município.Conclusão:é necessário maior investimento político e técnico para assegurar a adoção desse modelo nos diferentes setores e níveis de atenção do município.
RESUMENObjetivo:analizar las concepciones de los enfermeros en la vigilancia de la salud de los niños en las unidades de salud de la familia.Método:estudio cualitativo con el análisis temático de los datos, basado en el paradigma de la Vigilancia de la Salud. Se realizaron entrevistas con 13 enfermeras en la ciudad interior.Resultados:las enfermeras concibió la vigilancia de la salud del niño y la vigilancia activa, total, la identifi cación de riesgos/vulnerabilidades, a través de acciones multidisciplinario, intersectorial y dependiente de la participación materna. Encontramos lo desarrollo parcial de estos supuestos en la práctica, debido a las difi cultades, como la falta de participación de la madre en las acciones propuestas, la falta de tiempo para el debate y la adopción de medidas en las unidades y la falta de conexión entre los niveles y sectores en el condado.Conclusión:es necesaria una mayor inversión política y técnica para asegurar la adopción de este modelo en diferentes sectores y niveles de atención del municipio.
ABSTRACTObjective:to analyze conceptions of nurses on child health surveillance in family health units.Method:a qualitative study with thematic analysis of the data, based on the paradigm of Health Surveillance. Interviews were conducted with 13 nurses in a countryside city in the state of Sao Paulo.Results:nurses conceived child health surveillance as an active monitoring, which should be comprehensive, identifying risks/vulnerabilities, through multidisciplinary and intersectoral actions that are dependent on maternal involvement. We found partial development of these assumptions in practice, due to diffi culties such as lack of maternal involvement in the proposed actions, lack of time for discussion and adoption of measures in the units and disarticulation between levels and sectors of the city.Conclusion:a greater political and technical investment is needed to ensure the adoption of this model in different sectors and levels of care of the city.
Subject(s)
Humans , Male , Female , Middle Aged , Adrenal Cortex Hormones/pharmacokinetics , Bronchodilator Agents/pharmacokinetics , Budesonide/pharmacokinetics , Formoterol Fumarate/pharmacokinetics , Magnetic Resonance Imaging , Pulmonary Disease, Chronic Obstructive/pathology , Adrenal Cortex Hormones/administration & dosage , Bronchodilator Agents/administration & dosage , Budesonide/administration & dosage , Drug Combinations , Feasibility Studies , Forced Expiratory Volume/drug effects , Formoterol Fumarate/administration & dosage , Oxygen , Pulmonary Disease, Chronic Obstructive/drug therapy , Pulmonary Disease, Chronic Obstructive/physiopathology , Respiratory Function TestsABSTRACT
Background: Airway hyperresponsiveness (AHR) is the most characteristic feature of asthma, which is reported in COPD patients and smokers. Increased airway responsiveness to ί-agonists is also demonstrated in asthmatics as well as smokers. However, there is no report regarding AHR to ί-agonist drugs in COPD patients. Therefore, in this study pharmacologic bronchodilation response to salbutamol in COPD patients was examined. Materials and Methods: The threshold concentrations of inhaled salbutamol required for a 20% change in forced expiratory flow in 1 sec (FEV 1 ) as PC 20 , or a 35% change in specific airway conductance (sGaw) as PC 35 was measured in 14 COPD patients and 14 normal subjects. Results: Airway responsiveness to salbutamol in COPD patients (PC 20 = 14.14 ± 1.62 and PC 35 = 9.70 ± 1.48 mg/l) was significantly lower than normal subjects (PC 20 = 224.57 ± 16.62 and PC 35 = 81.87 ± 8.16 mg/l, P < 0.001 for both cases). The values of FEV 1 and sGaw in COPD patients (56.43 ± 14.45 and 0.081 ± 0.120 respectively) were significantly lower than those of normal subjects (104.07 ± 5.72 and 0.194 ± 0.041 respectively), (P < 0.001 for FEV 1 and P < 0.005 for sGaw). There was a significant correlation between FEV 1 with PC 20 salbutamol (r = 0.862, P < 0.001). The correlations between PC 20 and PC 35 was also statistically significant (r = 0.862, P < 0.001). Conclusion: These results showed increased airway responsiveness of most COPD patients to salbutamol which was highly correlated to airway caliber.
Subject(s)
Adult , Aged , Airway Remodeling/drug effects , Airway Resistance/drug therapy , Albuterol/pharmacokinetics , Albuterol/pharmacology , Anti-Asthmatic Agents/pharmacology , Anti-Asthmatic Agents/therapeutic use , Asthma/drug therapy , Asthma/physiopathology , Bronchi/drug effects , Bronchi/pharmacology , Bronchi/physiology , Bronchial Hyperreactivity/pharmacology , Bronchodilator Agents/pharmacokinetics , Bronchodilator Agents/pharmacology , Patients , Pulmonary Disease, Chronic Obstructive/drug therapy , Smoking/adverse effects , Smoking/complicationsABSTRACT
It has been demostrated that the effect of inhaled medications is enhanced by spacer devices, but their sizes make them unpractical to carry around and they have additional cost. In order to test if a homemade cheap spacer is as effective as the commercial spacers, we tested a small plastic bag with a cardboard mouth piece. We recluted 17 patients over 16 years of age with an obstructive ventilatory limitation in spirometry with a significative response with 200 µg of albuterol. We randomized patients into two groups: one received the bronchodilator through a commercial spacer and the other through the homemade device. We observed that with the latter we obtained similar or better FEV1 and FVC increases. We conclude that the use of this cheap device can be used in patients with advantage over commercial ones.
Se ha demostrado que el depósito y efecto de los medicamentos administrados a través de los inhaladores presurizados mejora con el uso de espaciadores, pero la adherencia a estos accesorios no es buena por su costo y por su tamaño incómodo. Nuestro objetivo fue determinar si un sistema artesanal tipo reservorio, armado con una bolsa plástica unida a una boquilla de cartón, es efectivo como espaciador. Para esto, seleccionamos a 17 sujetos mayores de 16 años con espirometría con limitación ventilatoria obstructiva y respuesta espirométrica significativa a 200 µg de salbutamol en aerosol presurizado. Se les asignó aleatoriamente a dos grupos: uno con aerocámara y otro con bolsa. Con esta última se obtuvo aumento del VEF1 y de la CVF post broncodilatador de mayor magnitud que con la aerocámara, con diferencia estadística significativa. Nos parece que estos resultados validan al sistema de la bolsa como espaciador de aerosoles presurizados para el uso de los pacientes.
Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged, 80 and over , Bronchodilator Agents/administration & dosage , Bronchodilator Agents/pharmacokinetics , Respiratory Tract Diseases/drug therapy , Inhalation Spacers , Administration, Inhalation , Albuterol/pharmacokinetics , Vital Capacity , Dose-Response Relationship, Drug , Forced Expiratory Volume , Single-Blind Method , Popular Work , PressureABSTRACT
O trabalho apresenta uma revisäo bibliográfica sobre dois agonistas ß2 seletivos, Salbutamol e Formoterol, no tratamento da asma leve e moderada, incluindo um breve estudo a respeito da classificaçäo e manifestaçöes clínicas da asma.
Subject(s)
Humans , Adult , Albuterol/pharmacokinetics , Albuterol/therapeutic use , Asthma/drug therapy , Asthma/metabolism , Adrenergic beta-Agonists/pharmacokinetics , Adrenergic beta-Agonists/therapeutic use , Bronchi/drug effects , Bronchi/metabolism , Bronchodilator Agents/pharmacokinetics , Bronchodilator Agents/therapeutic useABSTRACT
Recent reports have described a pathogenic role of nitric oxide in several reapiratory disease. It is specially useful in the adult respiratory distress syndrome, where it acts as a selective vasodilator and improves gas exchange, decreasing pulmonary shunting. Although it has a proven bronchodilator effect, its therapeutic role in diseases such as asthma and crhonic limitation of airway flow is not well defined. This article review the metabolism, mechanisms of action, potential uses and adverse effects of nitric oxide in respiratory disease
Subject(s)
Humans , Respiratory Tract Diseases/therapy , Nitric Oxide/therapeutic use , Asthma/therapy , Bronchodilator Agents/pharmacokinetics , Lung Diseases, Obstructive/therapy , Nitric Oxide/adverse effects , Nitric Oxide/physiology , Nitric Oxide/metabolism , Respiratory Distress Syndrome/therapyABSTRACT
En el presente trabajo revisamos el tratamiento actual del asma bronquial, proponiendo clasificación simple para catalogarla de acuerdo a la intensidad del cuadro tanto crónico como agudo. El objetivo de esta revisión es enfocar nuestros esfuerzos hacia un buen control ambiental, sobre todo intradomiciliario. En el proceso agudo recomendar el manejo de broncodilatadores principalmente por vía inhalada, por su rápida acción y para limitar sus efectos colaterales; siempre usarlos por razón necesaria, sin olvidar que durante la crisis hay inflamación importante, existiendo la posibilidad en cuadros de estado de mal asmático. Finalmente recalcar la importancia del manejo a largo plazo con el uso de antiinflamatorios tópicos